Neuroborreliosis treatment outcome study

At least 50% of patients with Lyme neuroborreliosis remain ...

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10/29/2015 · At least 50% of patients with Lyme neuroborreliosis remain ill years after treatment. There continues to be physicians who dispute the potential severity of Lyme disease and its ability to cause chronic illness in patients, even though there are an increasing number of evidence-based studies supporting that finding.

At least 50% of patients with Lyme neuroborreliosis remain ...

Lyme neuroborreliosis—epidemiology, diagnosis and ...

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7/28/2015 · Koedel and colleagues discuss the diagnosis and treatment of early and late Lyme neuroborreliosis, and review the controversies surrounding post …

Lyme neuroborreliosis—epidemiology, diagnosis and ...

Efficacy and safety of pharmacological treatments for Lyme ...

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9/29/2016 · The comprehensive systematic literature search included randomized-controlled trials (RCTs) and non-randomized studies (NRS) on treatment of Lyme neuroborreliosis in children (age <18 years). Our primary outcome was neurological symptoms after treatment. Risk of bias was assessed with the Cochrane risk of bias tools for RCTs and NRS.

Efficacy and safety of pharmacological treatments for Lyme ...

Neuroborreliosis - an overview | ScienceDirect Topics

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Neuroborreliosis can present with both acute and late manifestations. Some presentations include meningoencephalitis, cranial neuropathies, radiculopathy, and peripheral neuropathy. The entity of PLS is a controversial diagnosis. Antimicrobial therapy is first line for treatment of neuroborreliosis, with courses of therapy extending to 28 days ...

Neuroborreliosis - an overview | ScienceDirect Topics

Characteristics and Clinical Outcome of Lyme ...

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8/8/2017 · Despite a well-described symptomatology, treatment delay and sequelae are common in patients with Lyme neuroborreliosis (LNB). The aim of this study was to contribute to the knowledge about the symptomatology and epidemiology of LNB. ... we did not find any association between the type of antibiotic treatment and treatment outcome [7, 13, 35, 36].

Characteristics and Clinical Outcome of Lyme ...

Course and Outcome of Early European Lyme Neuroborreliosis ...

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Lyme Neuroborreliosis in Children A Prospective Study of Clinical features, Prognosis, and Outcome Article in The Pediatric Infectious Disease Journal 27(12):1089-94 · December 2008 with 40 Reads

Course and Outcome of Early European Lyme Neuroborreliosis ...

Lyme Neuroborreliosis in Children A Prospective Study of ...

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Abstract Background: Evaluation of children with clinically suspected neuroborreliosis (NB) is difficult. With a prospective study design we wanted to characterize children with signs and symptoms indicative for NB, investigate clinical outcome and, if possible, identify factors of importance for recovery.

Lyme Neuroborreliosis in Children A Prospective Study of ...

Lyme Neuroborreliosis in Children: A Prospective Study of ...

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10/21/2014 · Neuroborreliosis is a tick-borne infectious disease of the nervous system caused by Borrelia burgdorferi. Common clinical manifestations of neuroborreliosis are cranial nerve dysfunctions, polyradiculoneuritis, and meningitis. Diagnosis is usually based on clinical presentation, serologic testing, and analysis of cerebrospinal fluid. Many aspects of pharmacological treatment, such as choice of ...

Lyme Neuroborreliosis in Children: A Prospective Study of ...

Efficacy and safety of pharmacological treatments for ...

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7/9/2012 · The main purpose of this study is to determine whether four weeks treatment with oral doxycycline is as effective as three weeks treatment with intravenous ceftriaxone in patients with Lyme neuroborreliosis. The other purpose is to improve laboratory diagnostics of …

Efficacy and safety of pharmacological treatments for ...

Study of Lyme Neuroborreliosis - Full Text View ...

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Lyme neuroborreliosis is a late manifestation of an infection by Borrelia spp., a tick-borne bacterial pathogen that is known for causing Lyme disease and a range of clinical syndromes. The ailment is primarily seen during the summer months and symptoms range from headaches and facial nerve palsy to severe sensory and motor deficits with altered…

Study of Lyme Neuroborreliosis - Full Text View ...

Lyme Neuroborreliosis: Symptoms, Diagnosis and Treatment ...

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neuroborreliosis (LNB), the second most frequent LB manifestation in children. The aim of this prospective cohort study is to describe the occurrence of EM among children with LNB and to evaluate possible differences in clinical characteristics or outcome between LNB patients with and without EM.

Lyme Neuroborreliosis: Symptoms, Diagnosis and Treatment ...

Occurrence of erythema migrans in children with Lyme ...

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PDF | There have been few large reports of the treatment and outcome of neuroborreliosis in children. All 203 children with symptoms, cerebrospinal fluid and serologic findings compatible with ...

Occurrence of erythema migrans in children with Lyme ...

(PDF) Successful treatment of neuroborreliosis with ten ...

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treatment with 200 mg oral doxycycline per day or 2 g intravenous ceftriaxone per day. Our hypothesis was that oral doxycycline was not inferior to intravenous ceftriaxone with respect to clinical effi cacy in the treatment of European Lyme neuroborreliosis. As an outcome measure, a composite clinical score

(PDF) Successful treatment of neuroborreliosis with ten ...

Oral doxycycline versus intravenous ceftriaxone for ...

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1/29/2019 · This study evaluates the effect of written and oral information in a primary health care setting on 1) patients referred to specialised examination for Lyme neuroborreliosis, 2) delay from patient symptom debut to treatment for Lyme neuroborreliosis, and 3) number of Borrelia serology tests from primary health care.

Oral doxycycline versus intravenous ceftriaxone for ...

An Intervention in a Primary Healthcare Setting to Reduce ...

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The objective of this follow-up study was to determine the long-term outcome of strictly classified cases of neuroborreliosis treated with antibiotics. A 1-y prospective population-based survey of Lyme borreliosis was conducted in southern Sweden between 1992 and 1993. A total of 349 identified cases with suspected neuroborreliosis were followed up 5 y later.

An Intervention in a Primary Healthcare Setting to Reduce ...

5-y Follow-up Study of Patients with Neuroborreliosis ...

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8/10/2012 · Persistent symptoms after treatment of neuroborreliosis (NB) are well-documented, although the causative mechanisms are mainly unknown. The effect of repeated antibiotic treatment has not been studied in detail. The aim of this study was to determine whether: (1) persistent symptoms improve with doxycycline treatment; (2) doxycycline has an influence on systemic cytokine responses, and; (3 ...

5-y Follow-up Study of Patients with Neuroborreliosis ...

Doxycycline-mediated effects on persistent symptoms and ...

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12/17/2009 · Prevention of Lyme borreliosis. Prevention of Lyme borreliosis after a tick bite has been reported using a single dose of doxycycline as chemoprophylaxis in America [].In Europe, however, a comparable prophylactic treatment has not been evaluated with regard to I. ricinus tick bites.The best prophylactic strategy is to avoid a tick bite.

Doxycycline-mediated effects on persistent symptoms and ...

Treatment of Lyme borreliosis - PubMed Central (PMC)

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This is a summary of the American Academy of Neurology (AAN) guideline on treatment of nervous system Lyme disease and post-Lyme syndrome. The guideline addresses the use of antibiotic treatment in patients with nervous system Lyme disease and post-Lyme syndrome.

Treatment of Lyme borreliosis - PubMed Central (PMC)

TREATMENT OF NERVOUS SYSTEM LYME DISEASE

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10/21/2014 · Many aspects of pharmacological treatment, such as choice of drug, dosage, and duration are subject of intense debate, leading to uncertainties in patients and healthcare providers alike. To approach the questions regarding pharmacological treatment of neuroborreliosis, we will perform a systematic review.

TREATMENT OF NERVOUS SYSTEM LYME DISEASE

Efficacy and safety of pharmacological treatments for ...

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5/30/2018 · This indicates that Lyme neuroborreliosis decreases working capacity in a small fraction of patients, consistent with a Swedish study reporting a 12% rate of disabling sequelae five years after treatment for Lyme neuroborreliosis and with a Danish study that found a 5% rate of disability after a median 33 months of follow-up.3 9 Although living ...

Efficacy and safety of pharmacological treatments for ...

Lyme disease - Wikipedia

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8/15/2010 · However, one limitation is that our patients did not fully meet the diagnostic criteria for definite neuroborreliosis , because the Bb antibodies of immunoreaction in our study were nonspecific. In the present study, early intravenous antibiotic treatment for NB patients with central nervous systems involvement was beneficial.

Lyme disease - Wikipedia

Long term survival, health, social functioning, and ...

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2/1/2017 · B cell immunity, including the chemokine CXCL13, has an established role in Lyme neuroborreliosis, and also, T helper (Th) 17 immunity, including IL-17A, has recently been implicated. We analysed a set of cytokines and chemokines associated with B cell and Th17 immunity in cerebrospinal fluid and serum from clinically well-characterized patients with definite Lyme neuroborreliosis (group 1, …

Long term survival, health, social functioning, and ...

Acute neuroborreliosis with involvement of the central ...

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BACKGROUND: Evaluation of children with clinically suspected neuroborreliosis (NB) is difficult. With a prospective study design we wanted to characterize children with signs and symptoms ...

Acute neuroborreliosis with involvement of the central ...

Intrathecal Th17- and B cell-associated cytokine and ...

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Risk factors for a non-favourable outcome after treated European Neuroborreliosis. Randi Eikeland MD1 Åse Mygland MD PhD2 3 4 ... persistent infection is unlikely as prolonged antibiotic treatment does not improve the outcome permanently and is not recommended (7,17-20).

Intrathecal Th17- and B cell-associated cytokine and ...

Lyme neuroborreliosis in children: a prospective study of ...

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Knudtzen FC, Andersen NS, Jensen TG, Skarphédinsson S: Characteristics and clinical outcome of Lyme neuroborreliosis in high endemic area, 1995-2014: a retrospective cohort study in Denmark. Clin Infect Dis. 2017 Oct 16;65(9):1489-1495. Wormser GP, Dattwyler RJ, Shapior ED, et al.

Lyme neuroborreliosis in children: a prospective study of ...

Risk factors for a non-favourable outcome after treated ...

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1/21/2017 · Neuroborreliosis represents a relevant infectious disease and can cause a variety of neurological manifestations. Different stages and syndromes are described and atypical symptoms can result in diagnostic delay or misdiagnosis. The aim of this retrospective study was to define the pivotal neurological deficits in patients with neuroborreliosis that were the reason for admission in a hospital.

Risk factors for a non-favourable outcome after treated ...

Lyme Neuroborreliosis - Insights

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Lyme neuroborreliosis primarily leads to subacute lymphocytic meningitis.7 Antibiotic treatment improves neurological symptoms. However, studies on the long term outcome of Lyme neuroborreliosis are scarce and hampered by small study populations, short term follow-up, …

Lyme Neuroborreliosis - Insights

Common and uncommon neurological manifestations of ...

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Overview. The main purpose of this study is to determine whether four weeks treatment with oral doxycycline is as effective as three weeks treatment with intravenous ceftriaxone in …

Common and uncommon neurological manifestations of ...
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