Atbc cancer prevention study

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

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Welcome to the ATBC Study Web Site. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study was a cancer prevention trial conducted by the U.S. National Cancer Institute (NCI) and the National Institute for Health and Welfare of Finland from 1985 to 1993.The purpose of the study was to determine whether certain vitamin supplements would prevent lung cancer and other cancers in a ...

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

ATBC Study - Study Details - atbcstudy.cancer.gov

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The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study was conducted in Finland as a joint project between the National Institute for Health and Welfare of Finland and the US National Cancer Institute (NCI) . The overall design, rationale, objectives, and initial results of this intervention study have been published 1,2. Briefly ...

ATBC Study - Study Details - atbcstudy.cancer.gov

The alpha-tocopherol, beta-carotene lung cancer prevention ...

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The Alpha-Tocopherol, Beta-Carotene (ATBC) Lung Cancer Prevention Study was a randomized, double-blind, placebo-controlled, 2 x 2 factorial design, primary prevention trial testing the hypothesis that alpha-tocopherol (50 mg/day) and beta-carotene (20 mg/day) supplements reduce the incidence of lung cancer and possibly other cancers.

The alpha-tocopherol, beta-carotene lung cancer prevention ...

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

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The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study was conducted in Finland as a joint project between the National Public Health Institute of Finland and the NCI. The overall design, rationale, objectives, and initial results of this intervention study have been published. Briefly, this was a randomized, double-blind, placebo ...

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

The effect of vitamin E and beta carotene on the incidence ...

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4/14/1994 · METHODS: We performed a randomized, double-blind, placebo-controlled primary-prevention trial to determine whether daily supplementation with alpha-tocopherol, beta carotene, or both would reduce the incidence of lung cancer and other cancers.

The effect of vitamin E and beta carotene on the incidence ...

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC ...

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The project is a passive follow-up of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort. Originally, this was a large, randomized, double-blind, placebo-controlled, 2x2 factorial primary prevention trial testing the effects of alpha-tocopherol and beta-carotene supplementation on cancer incidence and mortality.

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC ...

The Effect of Vitamin E and Beta Carotene on the Incidence ...

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The ATBC Cancer Prevention Study Group. The alpha-tocopherol, beta-carotene lung cancer prevention study: design, methods, participant characteristics, and compliance.

The Effect of Vitamin E and Beta Carotene on the Incidence ...

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

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The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study conducted in southwestern Finland has been an integral cohort research resource for NCI for nearly three decades.

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

Selenium and Vitamin E Cancer Prevention Trial (SELECT ...

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There are many reasons why the vitamin E supplements may not have prevented prostate cancer. Two of the most likely reasons look back at the Alpha-Tocopherol Beta Carotene (ATBC) Cancer Prevention trial, a study designed to test vitamin E and beta carotene for lung cancer prevention in smokers (10).

Selenium and Vitamin E Cancer Prevention Trial (SELECT ...

Metabolomic Profiling of Serum Retinol in the Alpha ...

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9/6/2017 · The ATBC Cancer Prevention Study Group. The alpha-tocopherol, beta-carotene lung cancer prevention study: design, methods, participant characteristics, and compliance. Ann …

Metabolomic Profiling of Serum Retinol in the Alpha ...

β-Carotene and Lung Cancer: A Lesson for Future ...

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1/1/2003 · For example, secondary analyses in the ATBC Study indicated that vitamin E may reduce risk for colorectal and prostate cancer , which provided supporting evidence for initiating the Selenium and Vitamin E Cancer Prevention Trial (SELECT), a study designed to determine whether men who take selenium and vitamin E supplements have a lower risk of ...

β-Carotene and Lung Cancer: A Lesson for Future ...

What we study - Micronutrients - National Cancer Institute

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DCEG investigators are conducting in-depth research of several micronutrients including vitamins A, D, and E, and are coordinating multi-center, consortium efforts to address research gaps quickly. Examples of studies include: Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

What we study - Micronutrients - National Cancer Institute

Family history of prostate cancer and prostate cancer risk ...

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Study population. The ATBC Study was a placebo‐controlled, double‐blinded primary prevention trial with a 2 × 2 factorial design that tested the hypothesis of whether α‐tocopherol or β‐carotene supplementation would reduce the incidence of lung or other cancers in male smokers.

Family history of prostate cancer and prostate cancer risk ...

Metabolomics analysis of serum 25-hydroxy-vitamin D in the ...

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8/14/2016 · Shakira M Nelson, Orestis A Panagiotou, Gabriella M Anic, Alison M Mondul, Satu Männistö, Stephanie J Weinstein, Demetrius Albanes; Metabolomics analysis of serum 25-hydroxy-vitamin D in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study, International Journal of Epidemiology, Volume 45, Issue 5, 1 October 2016, Pages 1458 ...

Metabolomics analysis of serum 25-hydroxy-vitamin D in the ...

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC ...

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Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC ...

Nutrition Exam Flashcards | Quizlet

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Nutrition Exam. Chapters 8 - 15. STUDY. PLAY. ... heart disease cancer. type 1 diabetes. Research suggests that vitamin C supplements taken daily will reduce the incidence of the common cold. True False. ... (ATBC) Cancer Prevention Study indicated a decreased number of deaths among male smokers who took beta-carotene supplements.

Nutrition Exam Flashcards | Quizlet

Antioxidants and Cancer Prevention - National Cancer Institute

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In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., “Antioxidants and Cancer Prevention was originally published by the National Cancer Institute.” We welcome your comments on …

Antioxidants and Cancer Prevention - National Cancer Institute

Cancer prevention - Wikipedia

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Cancer prevention is the practice of taking active measures to decrease the incidence of cancer and mortality. The practice of prevention is dependent upon both individual efforts to improve lifestyle and seek preventative screening, and socioeconomic or public policy related to cancer prevention. Globalized cancer prevention is regarded as a critical objective due to its applicability to ...

Cancer prevention - Wikipedia

Association of seropositivity to Helicobacter species and ...

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We used a multiplex panel to assess whether seropositivity to 15 Helicobacter pylori proteins was associated with subsequent incidence of hepatobiliary cancers in the Finnish Alpha‐Tocopherol, Beta‐Carotene Cancer Prevention (ATBC) Study. We included 64 biliary cancers, 122 liver cancers, and 224 age‐matched controls which occurred over ...

Association of seropositivity to Helicobacter species and ...

A prospective analysis of telomere length and pancreatic ...

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5/15/2013 · Study population. The ATBC Study was a double‐blind, placebo‐controlled, 2 X 2 factorial‐primary prevention trial. The goal of the trial was to test whether alpha‐tocopherol or beta‐carotene supplementation reduced cancer incidence in Finnish male smokers. 27 The study design, data collection and methods have been described previously. 27 Briefly, 29,133 eligible men in …

A prospective analysis of telomere length and pancreatic ...

Prevention of Lung Cancer* - journal.chestnet.org

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shown in the -Tocopherol, -Carotene (ATBC) Lung Cancer Prevention Study3–5 and the -Carotene and Retinol Efficacy Trial (CARET).8,9 A similar trend was observed in a small study comparing -carotene and retinol (vitamin A) in asbestos workers,7 although the difference was not statistically significant.

Prevention of Lung Cancer* - journal.chestnet.org

Abstract 2183: Serum alpha-tocopherol, beta carotene and ...

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Abstract. Background: Tocopherols and carotenoids are naturally occurring antioxidants found in foods that have been shown to affect cancer incidence and progression in laboratory

Abstract 2183: Serum alpha-tocopherol, beta carotene and ...

ATBC - What does ATBC stand for? The Free Dictionary

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73] Conversely, no association between dietary intake of fruits, vegetables, carotenoids, flavonoids, vitamin E, and vitamin C and the risk of developing RCC was found in the ATBC (Alpha-Tocopherol, Beta-Carotene Cancer Prevention) study (27 062 male …

ATBC - What does ATBC stand for? The Free Dictionary

Association of Seropositivity to Helicobacter Species and ...

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Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Ethics Statement. The ATBC study was approved by the Institutional Review Boards of both the National Institutes of Health in the United States and the National Public Health Institute in Finland. ATBC was a randomized, double-blind, placebo-con-trolled primary prevention trial designed to ...

Association of Seropositivity to Helicobacter Species and ...

Vitamin D Status in the ATBC study & Cancer Mortality ...

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New study below [1]. "The Alpha-Tocopherol, Beta-Carotene (ATBC) Lung Cancer Prevention Study was a randomized, double-blind, placebo-controlled, 2 x 2 factorial design, primary prevention trial testing the hypothesis that alpha-tocopherol (50 mg/day) and beta-carotene (20 mg/day) supplements reduce the incidence of lung cancer and possibly other cancers.

Vitamin D Status in the ATBC study & Cancer Mortality ...

Increased Risk of Lung Cancer in Men with Tuberculosis in ...

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4/1/2011 · Study population. Subjects in the present study were enrolled in the ATBC study, a randomized, double-blind trial designed to assess whether supplementation with α-tocopherol and β-carotene reduces the risk of lung cancer ().The ATBC Study enrolled 29,133 men living in southwestern Finland in 1985–1988.

Increased Risk of Lung Cancer in Men with Tuberculosis in ...

Iron in Relation to Gastric Cancer in the Alpha-Tocopherol ...

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ATBC Cancer Prevention Study was approved by the institutional review boards of the National Cancer Insti-tute,Bethesda,Maryland,andtheNationalPublicHealth Institute, Helsinki, Finland. Study subjects Cases were subjects of the ATBC Study cohort who were diagnosed with gastric cancer through April 30, 2006, a follow-up of up to 21 years.

Iron in Relation to Gastric Cancer in the Alpha-Tocopherol ...

Multiple loci identified in a genome-wide association ...

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2/10/2008 · The Alpha Tocopherol Beta-Carotene Cancer Prevention study (ATBC) Study is supported by the Intramural Research Program of the National Cancer Institute, NIH, and …

Multiple loci identified in a genome-wide association ...

Clinical Trials Registry | Internet Stroke Center

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Trial Description. The Alpha-Tocopherol Beta-Carotene Cancer Prevention (ATBC) Study was a large randomized, double-blind, placebo-controlled, 2x2 factorial design, primary prevention trial testing the effects of alpha-tocopherol and beta-carotene supplements on cancer incidence and mortality conducted in Finland as a collaboration between the Public Health Institute (KTL) of Finland and the U ...

Clinical Trials Registry | Internet Stroke Center

Alpha-tocopherol, Beta-Carotene Lung Cancer Prevention ...

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AT and BC, both agents with strong antioxidant properties and low toxicity, protect against lung and other cancers. Capsule compliance was high (median = 99%). Beta carotene treatment did not result in a decrease in cancer at any of the major sites, but rather in an increase at several sites, most ...

Alpha-tocopherol, Beta-Carotene Lung Cancer Prevention ...

Beta-carotene did not work: aftermath of the ATBC study ...

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Introduction The Alpha-Tocopherol, Beta-Carotene Cancer Pre- vention Study (ATBC Study) was a double-blind trial testing the efficacy of a-tocopherol and carotene supplementation in prevention of lung cancer in par- ticular and cancer in general.

Beta-carotene did not work: aftermath of the ATBC study ...

Effects of a Combination of Beta Carotene and Vitamin A on ...

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In the ATBC Cancer Prevention Study, 876 new cases of lung cancer were diagnosed, yielding a relative risk of lung cancer of 1.18 among subjects who received beta carotene (with or without alpha ...

Effects of a Combination of Beta Carotene and Vitamin A on ...

Mitochondrial DNA Copy Number and Pancreatic Cancer in the ...

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cancer (19,20), no study has evaluated the role of mtDNA copy number and pancreatic cancer risk. Therefore, to better elucidate the relationship between mtDNA copy number and pancreatic cancer, we conducted a nested case-control study within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort of male smokers.

Mitochondrial DNA Copy Number and Pancreatic Cancer in the ...

Alpha-Tocopherol/Beta-Carotene lung cancer prevention study

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ATBC Alpha-Tocopherol/Beta-Carotene lung cancer prevention study. A trial assessing the effects, if any, of alpha-tocopherol and beta-carotene supplements on the ...

Alpha-Tocopherol/Beta-Carotene lung cancer prevention study

History/Timeline | Division of Cancer Prevention

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Alpha-Tocopherol, Beta Carotene (ATBC) Cancer Prevention Study Starts The purpose of the ATBC study was to determine whether certain vitamin supplements would prevent lung cancer and other cancers in a group of 29,133 male smokers in Finland.

History/Timeline | Division of Cancer Prevention

ATBC - Alpha-Tocopherol, Beta-Carotene (cancer prevention ...

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Stolzenberg-Solomon, PhD, and colleagues evaluated data from 29,092 men who participated in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, a placebo-controlled trial that sought to determine the effect of vitamin E and beta-carotene supplementation on the prevention of …

ATBC - Alpha-Tocopherol, Beta-Carotene (cancer prevention ...

Beta-Carotene: MedlinePlus Supplements

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The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 1994;330:1029-35. View abstract.

Beta-Carotene: MedlinePlus Supplements

Antioxidants and Cancer Prevention - OnHealth

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7/8/2005 · Post-trial follow-up has already been funded by NCI for CARET, ATBC, the Chinese Cancer Prevention Study, and the two smaller trials of skin cancer and colon polyps. Post-trial follow-up results have been published for ATBC, and as of July 2004 are in press for CARET and are in progress for the Chinese Cancer Prevention Study.

Antioxidants and Cancer Prevention - OnHealth

Genetics may influence the effects of vitamin E on cancer ...

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The ATBC Study is supported by the Intramural Research Program of the U.S. National Cancer Institute, National Institutes of Health, and by U.S. Public Health Service contract HHSN261201500005C ...

Genetics may influence the effects of vitamin E on cancer ...

ATBC Study Cancer (Atbcstudy.cancer.gov) - Alpha ...

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We collected one metadata history record for Atbcstudy.cancer.gov. ATBC Study Cancer has a poor description which rather negatively influences the efficiency of search engines index and hence worsens positions of the domain.

ATBC Study Cancer (Atbcstudy.cancer.gov) - Alpha ...

Alpha-Tocopherol, Beta-Carotene - How is Alpha-Tocopherol ...

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The Physicians' Health Study, the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) trial, the Beta-Carotene and Retinol Efficacy Trial (CARET), and other trials found no overall effect of [beta]-carotene on cancer (3).

Alpha-Tocopherol, Beta-Carotene - How is Alpha-Tocopherol ...

Carotene and Retinol Efficacy Trial (CARET)

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The Carotene and Retinol Efficacy Trial (CARET) was a randomized, double-blind, placebo-controlled trial of the cancer prevention efficacy and safety of a daily combination of 30 milligrams (mg) of beta-carotene and 25,000 IU of retinyl palmitate in 18,314 persons who were at high risk for lung cancer.

Carotene and Retinol Efficacy Trial (CARET)

Metabolomic analysis of prostate cancer risk in a ...

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To this end, we conducted a prospective analysis of prostate cancer within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study cohort based on 200 cases (100 aggressive) and 200 controls (age- and blood collection date-matched) with fasting serum collected up to 20 years prior to case diagnoses.

Metabolomic analysis of prostate cancer risk in a ...

ATBC Publications | PubFacts

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Introduction: The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study demonstrated that β-carotene supplementation increases lung cancer incidence in smokers. Further, cigarettes with higher tar and nicotine content are associated with a higher risk of lung cancer.

ATBC Publications | PubFacts
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